Promethazine HCl and Codeine Phosphate Oral Answer ought to be utilised with caution in individuals with bone- marrow despair. Leukopenia and agranulocytosis have already been noted, generally when promethazine has long been used in association with other recognised marrow-harmful agents.
Your healthcare provider could do blood assessments to look for adrenal gland difficulties. Connect with your Health care provider immediately For those who have any of such indicators:
Browse the Medication Tutorial if accessible out of your pharmacist before you start having this product or service and every time you obtain a refill. When you have any inquiries, inquire your physician or pharmacist.
It truly is soluble in water and freely soluble in Liquor. The molecular weight is 320.88. Its molecular method is C17H20N2S•HCl, and it has the next chemical composition.
Do not take promethazine/codeine unless it's been prescribed to you personally by a Health care supplier. Just take it as prescribed.
Excessively huge dosages of antihistamines, which includes promethazine hydrochloride, in pediatric individuals may perhaps bring about sudden death (see OVERDOSAGE). Hallucinations and convulsions have happened with therapeutic doses and overdoses of promethazine hydrochloride in pediatric individuals. In pediatric patients that are acutely ill linked with dehydration, There is certainly an increased susceptibility to dystonias with the usage of promethazine HCl.
A monoamine oxidase inhibitor (MAOI) within the past two weeks, and that is a medicine ordinarily utilized for despair or Parkinson’s ailment
Inform your healthcare service provider Should your cough will not recuperate just after 5 times of getting promethazine/codeine. They can need to have to examine to view if something else is causing the cough.
Keep at space temperature away from light-weight and dampness. Don't retail store in the bathroom. Do not freeze liquid varieties of this medication. Hold all drugs away from small children and pets.
The mixture of promethazine hydrochloride website and codeine phosphate is contraindicated in pediatric people lower than 6 several years of age. Concomitant administration of promethazine products with other respiratory depressants has an association with respiratory depression, and read more at times Demise, in pediatric clients. The Affiliation does in a roundabout way relate to individualized weight-primarily based dosing, which might normally permit Risk-free administration.
Stimulation may very well be evident, especially in young children and geriatric clients. Convulsions may well almost never here occur. A paradoxical reaction continues to be reported in kids receiving more info single doses of 75 mg to a hundred twenty five mg orally, characterised by hyperexcitability and nightmares.
Disposal of Unused Promethazine HCl and Codeine Phosphate Oral Solution Advise individuals to appropriately get rid of unused Promethazine HCl and Codeine Phosphate Oral Resolution. Suggest clients to toss the drug from the domestic trash following these steps. 1) Eliminate them from their unique containers and mix them with an undesirable substance, like used coffee grounds or kitty litter (this makes the drug much less attractive to youngsters and pets, and unrecognizable to individuals who might intentionally go in the trash trying to get prescription drugs).
Codeine has excellent antitussive action, Despite the fact that below that of morphine at equivalent doses. It truly is Utilized in choice to morphine, due to the fact Uncomfortable side effects are rare at the standard antitussive dose of codeine.
If your individual develops these signals or indicators, elevate the dose for the former degree and get more info taper extra little by little, possibly by growing the interval involving decreases, lowering the amount of transform in dose, or both.